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KMID : 0387519920020010119
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Journal of Maryknoll Hospital
1992 Volume.2 No. 1 p.119 ~ p.128
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Clinical and Histopathologic Finding of Pathergy of Pathergy Test Sites in Patients with Behcet' s Disease
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Abstract
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through the clinicopathologic study of pathergy test sites of 16 patients with Behcet's disease in the active or inactive stage, the following results were obtained;
1. In the active stage, six of 16 patients(37.5%) showed positive reactions in clinical pathergy tests, which are much higher than in the inactive stage when only one patient showed a positive reaction. The severity of the clinical pathergy
reaction
was directly to the activity of the disease.
2. The characteristic histopathologic finding in the active stage was a dermal inflammatory cellular infiltration composed mainly of polymorphonuclear leukocytes and of lymphomononuclear cells accompanied by leukocytoclasia. Two of patients
showed
true
leukocytoclastic vasculitis.
3. Although the type of disease and the reactivity of the clinical pathergy test were related in terms of the severity of the histopathologic findings, there were some notible histopathologic changes even in the cases with negative clinical
pathergy
reaction.
We concluded that the histopathologic findings of the pathergy test sites were more reliable for the diagnosis of Behcet's disease than the clinical findings.
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KEYWORD
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